| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
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| Ligand | BDBM50436562 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_966955 (CHEMBL2401340) |
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| IC50 | 230±n/a nM |
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| Citation |  Suchaud, V; Gavara, L; Saugues, E; Nauton, L; Théry, V; Anizon, F; Moreau, P Identification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors. Bioorg Med Chem21:4102-11 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-3 |
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| Name: | Serine/threonine-protein kinase pim-3 |
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| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
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| Type: | Protein |
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| Mol. Mass.: | 35888.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86V86 |
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| Residue: | 326 |
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| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
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| BDBM50436562 |
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| n/a |
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| Name | BDBM50436562 |
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| Synonyms: | CHEMBL2397525 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H7ClN4O2 |
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| Mol. Mass. | 286.673 |
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| SMILES | [O-][N+](=O)c1cc2n[nH]cc2c2c1[nH]c1ccc(Cl)cc21 |
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| Structure | 
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