| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM50436904 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_971691 (CHEMBL2404230) |
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| Ki | 8.0±n/a nM |
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| Citation |  Pi, Z; Sutton, J; Lloyd, J; Hua, J; Price, L; Wu, Q; Chang, M; Zheng, J; Rehfuss, R; Huang, CS; Wexler, RR; Lam, PY 2-Aminothiazole based P2Y(1) antagonists as novel antiplatelet agents. Bioorg Med Chem Lett23:4206-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50436904 |
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| n/a |
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| Name | BDBM50436904 |
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| Synonyms: | CHEMBL2401859 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24F3N3O2S |
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| Mol. Mass. | 499.548 |
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| SMILES | COc1ccc(cc1)-c1sc(Nc2cccnc2Oc2ccccc2C(C)(C)C)nc1C(F)(F)F |
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| Structure | 
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