| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 2 |
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| Ligand | BDBM32203 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_972463 (CHEMBL2412833) |
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| IC50 | 2030±n/a nM |
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| Citation |  Wangtrakuldee, P; Byrd, MS; Campos, CG; Henderson, MW; Zhang, Z; Clare, M; Masoudi, A; Myler, PJ; Horn, JR; Cotter, PA; Hagen, TJ Discovery of Inhibitors of ACS Med Chem Lett4:699-703 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 2 |
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| Name: | Methionine aminopeptidase 2 |
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| Synonyms: | Initiation factor 2-associated 67 kDa glycoprotein | MAP 2 | MAP2_HUMAN | METAP2 | MNPEP | MetAP 2 | Methionine aminopeptidase 2 (MetAP2) | Methionine aminopeptidases (HsMetAP2) | P67EIF2 | Peptidase M 2 | p67 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52884.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50579 |
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| Residue: | 478 |
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| Sequence: | MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
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| BDBM32203 |
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| n/a |
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| Name | BDBM32203 |
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| Synonyms: | 8-quinolinol | CHEMBL310555 | US10005735, Table 1.7 | US9394254, 6 | cid_1923 | oxine | quinolin-8-ol |
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| Type | Small organic molecule |
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| Emp. Form. | C9H7NO |
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| Mol. Mass. | 145.158 |
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| SMILES | Oc1cccc2cccnc12 |
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| Structure | 
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