| Reaction Details |
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 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 [K65Q] |
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| Ligand | BDBM50437458 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_974577 (CHEMBL2410165) |
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| IC50 | 1188±n/a nM |
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| Citation |  Wang, QQ; Cheng, N; Zheng, XW; Peng, SM; Zou, XQ Synthesis of organic nitrates of luteolin as a novel class of potent aldose reductase inhibitors. Bioorg Med Chem21:4301-10 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldo-keto reductase family 1 member B1 [K65Q] |
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| Name: | Aldo-keto reductase family 1 member B1 [K65Q] |
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| Synonyms: | AKR1B1 | ALDR_BOVIN | Aldose reductase |
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| Type: | Protein |
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| Mol. Mass.: | 35916.27 |
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| Organism: | Bos taurus (Cattle) |
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| Description: | P16116[K65Q] |
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| Residue: | 315 |
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| Sequence: | AHNIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQA
KLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKD
FFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPA
VNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKY
NKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWRACAL
VSCASHRDYPFHEEF
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| BDBM50437458 |
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| n/a |
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| Name | BDBM50437458 |
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| Synonyms: | CHEMBL2409350 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16O6 |
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| Mol. Mass. | 340.3267 |
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| SMILES | CCOc1cc(O)c2c(c1)oc(cc2=O)-c1ccc2OCCOc2c1 |
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| Structure | 
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