Reaction Details |
| Report a problem with these data |
Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
---|
Ligand | BDBM50437708 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_974635 (CHEMBL2410561) |
---|
IC50 | 4000±n/a nM |
---|
Citation | Moore, JD; Potter, A Pin1 inhibitors: Pitfalls, progress and cellular pharmacology. Bioorg Med Chem Lett23:4283-91 (2013) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
---|
Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Type: | PROTEIN |
Mol. Mass.: | 18248.11 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1502595 |
Residue: | 163 |
Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
|
|
|
BDBM50437708 |
---|
n/a |
---|
Name | BDBM50437708 |
Synonyms: | CHEMBL2409073 |
Type | Small organic molecule |
Emp. Form. | C20H16FN5O |
Mol. Mass. | 361.3723 |
SMILES | Fc1cccc(C[C@@H](NC(=O)c2ccc3ccccc3c2)c2nnn[nH]2)c1 |r| |
Structure |
|