Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1
LigandBDBM50437709
Substrate/Competitorn/a
Meas. Tech.ChEMBL_974635 (CHEMBL2410561)
IC50 890±n/a nM
Citation Moore, JDPotter, A Pin1 inhibitors: Pitfalls, progress and cellular pharmacology. Bioorg Med Chem Lett23:4283-91 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Name:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Synonyms:PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Type:PROTEIN
Mol. Mass.:18248.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1502595
Residue:163
Sequence:
MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50437709
n/a
NameBDBM50437709
Synonyms:CHEMBL2409074
TypeSmall organic molecule
Emp. Form.C23H20FNO3
Mol. Mass.377.4082
SMILESOC(=O)C[C@@H](C\C=C\c1cccc(F)c1)NC(=O)c1ccc2ccccc2c1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: