| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
|---|
| Ligand | BDBM50364141 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_977607 (CHEMBL2423574) |
|---|
| IC50 | 7.8±n/a nM |
|---|
| Citation |  Mente, S; Arnold, E; Butler, T; Chakrapani, S; Chandrasekaran, R; Cherry, K; DiRico, K; Doran, A; Fisher, K; Galatsis, P; Green, M; Hayward, M; Humphrey, J; Knafels, J; Li, J; Liu, S; Marconi, M; McDonald, S; Ohren, J; Paradis, V; Sneed, B; Walton, K; Wager, T Ligand-protein interactions of selective casein kinase 1d inhibitors. J Med Chem56:6819-28 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase I isoform delta |
|---|
| Name: | Casein kinase I isoform delta |
|---|
| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 47356.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48730 |
|---|
| Residue: | 415 |
|---|
| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
|
|
|
|---|
| BDBM50364141 |
|---|
| n/a |
|---|
| Name | BDBM50364141 |
|---|
| Synonyms: | CHEMBL1951415 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20FN5 |
|---|
| Mol. Mass. | 337.394 |
|---|
| SMILES | Nc1nccc(n1)-c1c(ncn1C1CCCCC1)-c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
