| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM50439495 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_979349 (CHEMBL2423040) |
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| IC50 | 67000±n/a nM |
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| Citation |  Keffer, JL; Huecas, S; Hammill, JT; Wipf, P; Andreu, JM; Bewley, CA Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria. Bioorg Med Chem21:5673-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_STAAU | ftsZ |
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| Type: | Protein |
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| Mol. Mass.: | 41023.36 |
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| Organism: | Staphylococcus aureus |
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| Description: | P0A031 |
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| Residue: | 390 |
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| Sequence: | MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQ
IGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKI
AKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMM
EAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEA
AKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINP
ELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDS
VSERTHTTKEDDIPSFIRNREERRSRRTRR
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| BDBM50439495 |
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| n/a |
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| Name | BDBM50439495 |
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| Synonyms: | CHEMBL2418095 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H24Cl4O8 |
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| Mol. Mass. | 678.34 |
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| SMILES | Oc1cc(O)c2Oc3cc(C\C=C(Cl)/Cc4cc(O)c(Oc5cc(C\C=C(Cl)/Cc2c1)c(O)cc5Cl)c(O)c4)c(O)cc3Cl |t:11,25| |
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| Structure | 
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