| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 3 |
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| Ligand | BDBM50439673 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_977739 |
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| IC50 | 2.0±n/a nM |
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| Citation |  Kalin JH; Bergman JA Development and therapeutic implications of selective histone deacetylase 6 inhibitors. J Med Chem 56:6297-313 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 3 |
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| Name: | Histone deacetylase 1/2/3 |
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| Synonyms: | HD3 | Histone deacetylase 3 (HDAC3) | Human HDAC3 | RPD3-2 | SMAP45 |
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| Type: | Enzyme |
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| Mol. Mass.: | 48829.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 428 |
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| Sequence: | MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR
FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN
KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA
FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI
NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV
RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ
TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN
DKESDVEI
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| BDBM50439673 |
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| n/a |
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| Name | BDBM50439673 |
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| Synonyms: | CHEMBL2417782 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H30N4O5S |
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| Mol. Mass. | 462.562 |
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| SMILES | CC(C)(C)OC(=O)Nc1cccc(c1)-c1csc(NC(=O)CCCCCCC(=O)NO)n1 |
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| Structure | 
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