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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Ghrelin receptor | ||
| Ligand | BDBM50440252 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_982014 | ||
| Ki | 3.3±n/a nM | ||
| Citation |  McClure KF; Jackson M; Cameron KO; Kung DW; Perry DA; Orr ST; Zhang Y; Kohrt J; Tu M; Gao H; Fernando D; Jones R; Erasga N; Wang G; Polivkova J; Jiao W; Swartz R; Ueno H; Bhattacharya SK; Stock IA; Varma S; Bagdasarian V; Perez S; Kelly-Sullivan D; Wang R; Kong J; Cornelius P; Michael L; Lee E; Janssen A; Steyn SJ; Lapham K; Goosen T Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor. Bioorg Med Chem Lett 23:5410-4 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Ghrelin receptor | |||
| Name: | Ghrelin receptor | ||
| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | Ghrelin receptor 1a (GHS-R1a) | ||
| Type: | Receptor | ||
| Mol. Mass.: | 41334.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a. | ||
| Residue: | 366 | ||
| Sequence: |
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| BDBM50440252 | |||
| n/a | |||
| Name | BDBM50440252 | ||
| Synonyms: | CHEMBL2426686 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H30N6O2 | ||
| Mol. Mass. | 458.5554 | ||
| SMILES | COc1ccc(CC(=O)N2CCC3(CN(C3)[C@@H]3CCc4cc(ccc34)-n3nccn3)CC2)nc1 |r| | ||
| Structure | 
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