| Reaction Details |
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 | Report a problem with these data |
| Target | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Ligand | BDBM50085526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_982298 (CHEMBL2429516) |
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| IC50 | 37100±n/a nM |
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| Citation |  St John, SE; Jensen, KC; Kang, S; Chen, Y; Calamini, B; Mesecar, AD; Lipton, MA Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2. Bioorg Med Chem21:6022-37 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Synonyms: | Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Type: | Protein |
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| Mol. Mass.: | 25917.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16083 |
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| Residue: | 231 |
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| Sequence: | MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
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| BDBM50085526 |
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| n/a |
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| Name | BDBM50085526 |
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| Synonyms: | (E)-3,5,30,40-Tetramethoxystilbene | 4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-1,2-dimethoxybenzene | 4-[2-(3,5-dimethoxyphenyl)-(E)-1-ethenyl]-1,2-dimethoxybenzene | CHEMBL44509 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20O4 |
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| Mol. Mass. | 300.349 |
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| SMILES | COc1cc(OC)cc(\C=C\c2ccc(OC)c(OC)c2)c1 |
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| Structure | 
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