| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ribosyldihydronicotinamide dehydrogenase [quinone] |
|---|
| Ligand | BDBM50440274 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_982298 (CHEMBL2429516) |
|---|
| IC50 | 25500±n/a nM |
|---|
| Citation |  St John, SE; Jensen, KC; Kang, S; Chen, Y; Calamini, B; Mesecar, AD; Lipton, MA Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2. Bioorg Med Chem21:6022-37 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ribosyldihydronicotinamide dehydrogenase [quinone] |
|---|
| Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
|---|
| Synonyms: | Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone] |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 25917.25 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P16083 |
|---|
| Residue: | 231 |
|---|
| Sequence: | MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
|
|
|
|---|
| BDBM50440274 |
|---|
| n/a |
|---|
| Name | BDBM50440274 |
|---|
| Synonyms: | CHEMBL2426748 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H12O4 |
|---|
| Mol. Mass. | 256.2534 |
|---|
| SMILES | Oc1ccc(cc1)C(\C=O)=C/c1cc(O)cc(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
