| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase C |
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| Ligand | BDBM50440293 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_982570 (CHEMBL2428215) |
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| Ki | 118±n/a nM |
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| Citation |  Malesevic, M; Gutknecht, D; Prell, E; Klein, C; Schumann, M; Nowak, RA; Simon, JC; Schiene-Fischer, C; Saalbach, A Anti-inflammatory effects of extracellular cyclosporins are exclusively mediated by CD147. J Med Chem56:7302-11 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase C |
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| Name: | Peptidyl-prolyl cis-trans isomerase C |
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| Synonyms: | CYPC | Cyclophilin C (CypC) | PPIC | PPIC_HUMAN | Peptidyl-prolyl cis-trans isomerase C |
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| Type: | Protein |
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| Mol. Mass.: | 22767.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P45877 |
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| Residue: | 212 |
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| Sequence: | MGPGPRLLLPLVLCVGLGALVFSSGAEGFRKRGPSVTAKVFFDVRIGDKDVGRIVIGLFG
KVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMIQGGDITTGDGTGGVSIYGETFPDE
NFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVIDGMTVVHSIELQA
TDGHDRPLTNCSIINSGKIDVKTPFVVEIADW
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| BDBM50440293 |
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| n/a |
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| Name | BDBM50440293 |
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| Synonyms: | CHEMBL2424822 |
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| Type | Small organic molecule |
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| Emp. Form. | C67H111N13O14 |
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| Mol. Mass. | 1322.6769 |
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| SMILES | CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)Cc2nc3ccc(cc3[nH]2)C(O)=O)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C |r| |
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| Structure | 
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