| Reaction Details |
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 | Report a problem with these data |
| Target | Lethal(3)malignant brain tumor-like protein 4 |
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| Ligand | BDBM50440606 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_983407 (CHEMBL2429077) |
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| IC50 | >10000±n/a nM |
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| Citation |  James, LI; Korboukh, VK; Krichevsky, L; Baughman, BM; Herold, JM; Norris, JL; Jin, J; Kireev, DB; Janzen, WP; Arrowsmith, CH; Frye, SV Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3. J Med Chem56:7358-71 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lethal(3)malignant brain tumor-like protein 4 |
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| Name: | Lethal(3)malignant brain tumor-like protein 4 |
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| Synonyms: | H-l(3)mbt-like protein 4 | L(3)mbt-like protein 4 | L3MBTL4 | LMBL4_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 71132.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_983407 |
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| Residue: | 623 |
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| Sequence: | MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
RVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
ILMFRHSQELPEEDIASGQEVRG
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| BDBM50440606 |
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| n/a |
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| Name | BDBM50440606 |
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| Synonyms: | CHEMBL2426376 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H39N5O2 |
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| Mol. Mass. | 537.6951 |
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| SMILES | CCN1Cc2ccc(NC(=O)c3ccc(cc3Nc3ccccc3)C(=O)N3CCC(CC3)C3CCCN3)cc2C1 |
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| Structure | 
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