| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxoacyl-[acyl-carrier-protein] reductase |
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| Ligand | BDBM50440627 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_983602 (CHEMBL2427114) |
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| IC50 | >100000±n/a nM |
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| Citation |  Belluti, F; Perozzo, R; Lauciello, L; Colizzi, F; Kostrewa, D; Bisi, A; Gobbi, S; Rampa, A; Bolognesi, ML; Recanatini, M; Brun, R; Scapozza, L; Cavalli, A Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI). J Med Chem56:7516-26 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| 3-oxoacyl-[acyl-carrier-protein] reductase |
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| Name: | 3-oxoacyl-[acyl-carrier-protein] reductase |
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| Synonyms: | 3-oxoacyl-(Acyl-carrier protein) reductase | FabG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33360.55 |
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| Organism: | Plasmodium falciparum (isolate 3D7) |
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| Description: | ChEMBL_107660 |
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| Residue: | 301 |
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| Sequence: | MSVLHRFYLFFLFTKFFHCYKISYVLKNAKLAPNHAIKNINSLNLLSENKKENYYYCGEN
KVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVSK
KEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQPIS
KRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPG
FISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDGGLS
P
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| BDBM50440627 |
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| n/a |
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| Name | BDBM50440627 |
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| Synonyms: | CHEMBL2426553 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9ClO6 |
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| Mol. Mass. | 320.681 |
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| SMILES | Oc1cc(O)c2cc(Oc3ccc(Cl)cc3O)c(=O)oc2c1 |
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| Structure | 
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