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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H2 receptor | ||
| Ligand | BDBM50440988 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_985420 (CHEMBL2432449) | ||
| Ki | 6268±n/a nM | ||
| Citation |  Banister, SD; Manoli, M; Barron, ML; Werry, EL; Kassiou, M N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes ass receptor ligands with potential neuroprotective effects. Bioorg Med Chem21:6038-52 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histamine H2 receptor | |||
| Name: | Histamine H2 receptor | ||
| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40115.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 359 | ||
| Sequence: |
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| BDBM50440988 | |||
| n/a | |||
| Name | BDBM50440988 | ||
| Synonyms: | CHEMBL2432039 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H23N | ||
| Mol. Mass. | 277.4033 | ||
| SMILES | C(N[C@@H]1C2C3CC4C5CC(C2C35)C14)C12C3C4C5C3C1C5C24 |r,wD:2.1,THB:4:11:8:12.6,5:6:10.11:8,3:10:8:12.6,2:12:10.11:8,(10.9,-13.99,;9.58,-14.73,;8.29,-13.96,;6.29,-14.03,;6.86,-12.77,;8.75,-12.79,;8.76,-11.28,;7.43,-10.5,;7.16,-9.13,;7.03,-11.8,;5.75,-12.37,;6.36,-11.25,;8.28,-12.33,;12.2,-14.76,;12.68,-15.28,;12.43,-17.17,;14.33,-17.29,;14.59,-15.38,;14.08,-14.88,;13.83,-16.78,;11.94,-16.66,)| | ||
| Structure | 
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