| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein delta homolog 1 |
|---|
| Ligand | BDBM50441567 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_988747 |
|---|
| Kd | 70±n/a nM |
|---|
| Citation |  Goodfellow VS; Loweth CJ; Ravula SB; Wiemann T; Nguyen T; Xu Y; Todd DE; Sheppard D; Pollack S; Polesskaya O; Marker DF; Dewhurst S; Gelbard HA Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem 56:8032-48 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein delta homolog 1 |
|---|
| Name: | Protein delta homolog 1 |
|---|
| Synonyms: | DLK-1 | FA1 | Fetal antigen 1 | pG2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41294.81 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1444684 |
|---|
| Residue: | 383 |
|---|
| Sequence: | MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTS
PGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNRTCVSLDDGLYECSCAPGYS
GKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCE
NDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFT
GLTCVKKRALSPQQVTRLPSGYGLAYRLTPGVHELPVQQPEHRILKVSMKELNKKTPLLT
EGQAICFTILGVLTSLVVLGTVGIVFLNKCETWVSNLRYNHMLRKKKNLLLQYNSGEDLA
VNIIFPEKIDMTTFSKEAGDEEI
|
|
|
|---|
| BDBM50441567 |
|---|
| n/a |
|---|
| Name | BDBM50441567 |
|---|
| Synonyms: | CHEMBL2436978 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H27N5 |
|---|
| Mol. Mass. | 421.5368 |
|---|
| SMILES | CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
