| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Papain |
|---|
| Ligand | BDBM50157741 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_988143 (CHEMBL2439234) |
|---|
| IC50 | 7.0±n/a nM |
|---|
| Citation |  Ribeiro, CJ; Kumar, SP; Gut, J; Gonçalves, LM; Rosenthal, PJ; Moreira, R; Santos, MM Squaric acid/4-aminoquinoline conjugates: novel potent antiplasmodial agents. Eur J Med Chem69:365-72 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Papain |
|---|
| Name: | Papain |
|---|
| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 38923.01 |
|---|
| Organism: | Carica papaya |
|---|
| Description: | Papain was purchased from Sigma, Germany. |
|---|
| Residue: | 345 |
|---|
| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
|
|
|
|---|
| BDBM50157741 |
|---|
| n/a |
|---|
| Name | BDBM50157741 |
|---|
| Synonyms: | CHEMBL374508 | E-64 | E64 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H27N5O5 |
|---|
| Mol. Mass. | 357.4054 |
|---|
| SMILES | [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H]-1-[#8]-[#6@@H]-1-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7] |r| |
|---|
| Structure | 
|
|---|
Search and Browse
