| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vitamin D3 receptor |
|---|
| Ligand | BDBM50441911 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_987815 (CHEMBL2437763) |
|---|
| Ki | 2840±n/a nM |
|---|
| Citation |  Ali, AR; El-Bendary, ER; Ghaly, MA; Shehata, IA Novel acetamidothiazole derivatives: synthesis and in vitro anticancer evaluation. Eur J Med Chem69:908-19 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vitamin D3 receptor |
|---|
| Name: | Vitamin D3 receptor |
|---|
| Synonyms: | 1,25-dihydroxyvitamin D3 receptor | NR1I1 | Nuclear receptor subfamily 1 group I member 1 | Retinoic acid receptor RXR-alpha/Vitamin D3 receptor | VDR | VDR_HUMAN |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 48288.72 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11473 |
|---|
| Residue: | 427 |
|---|
| Sequence: | MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
VFGNEIS
|
|
|
|---|
| BDBM50441911 |
|---|
| n/a |
|---|
| Name | BDBM50441911 |
|---|
| Synonyms: | CHEMBL2437294 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H22N4O2S |
|---|
| Mol. Mass. | 358.458 |
|---|
| SMILES | CC(=O)N1CCN(CC1)C(=O)Cn1c(csc1=N)-c1ccc(C)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
