| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50441937 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_987953 (CHEMBL2438376) |
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| Ki | 2435±n/a nM |
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| Citation |  Abate, C; Selivanova, SV; Müller, A; Krämer, SD; Schibli, R; Marottoli, R; Perrone, R; Berardi, F; Niso, M; Ametamey, SM Development of 3,4-dihydroisoquinolin-1(2H)-one derivatives for the Positron Emission Tomography (PET) imaging ofs2 receptors. Eur J Med Chem69:920-30 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50441937 |
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| n/a |
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| Name | BDBM50441937 |
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| Synonyms: | CHEMBL2437387 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N2O4 |
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| Mol. Mass. | 410.506 |
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| SMILES | COc1cccc2C(=O)N(CCCN3CCc4cc(OC)c(OC)cc4C3)CCc12 |
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| Structure | 
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