| Reaction Details |
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 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
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| Ligand | BDBM50442345 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_990950 (CHEMBL2445278) |
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| IC50 | 170±n/a nM |
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| Citation |  Kato, A; Okaki, T; Ifuku, S; Sato, K; Hirokami, Y; Iwaki, R; Kamori, A; Nakagawa, S; Adachi, I; Kiria, PG; Onomura, O; Minato, D; Sugimoto, K; Matsuya, Y; Toyooka, N Synthesis and biological evaluation of N-(2-fluorophenyl)-2ß-deoxyfuconojirimycin acetamide as a potent inhibitor fora-l-fucosidases. Bioorg Med Chem21:6565-73 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tissue alpha-L-fucosidase |
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| Name: | Tissue alpha-L-fucosidase |
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| Synonyms: | Alpha-L-fucosidase I | FUCO_RAT | Fuca | Fuca1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53482.81 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_990950 |
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| Residue: | 462 |
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| Sequence: | MWDLKSEWWAVGFGLLLLLAASAQAGGLAPHHYTPDWPSLDSRPLPRWFDEAKFGLFVHW
GVYSVPAWGSEWFWWHWQGEQSSAYVRFMKENYPPGFSYADFAPQFTARFFHPEEWADLF
QAAGAKYVVLTAKHHEGFTNWPSAVSWNWNSKDVGPHRDLVGELGAAVRKRNIRYGLYHS
LFEWFHPLYLLDKKNGLKTQHFVSTKTMPELYDLVNRYKPDLIWSDGEWECPDSYWNSTE
FLAWLYNESPVKDQVVVNDRWGQNCSCRHGGYYNCEDKYRPHSLPDHKWEMCTSVDKASW
GYRRDMSMSTIVDENEIIEELVQTISLGGNYLLNIGPNKDGVIVPIFQERLLAVGKWLQI
NGEAIYASKPWRVQSERNKTVVWYTTKDSAVYATFLHWPEDGVVNLQSPKMTSATKITML
GMEGELHWTQDPLEGVLITLPQLPPGTFPVESAWTLKLTKVN
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| BDBM50442345 |
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| n/a |
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| Name | BDBM50442345 |
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| Synonyms: | CHEMBL2442782 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22N2O4 |
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| Mol. Mass. | 294.3462 |
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| SMILES | C[C@@H]1N[C@H](CC(=O)Nc2cccc(C)c2)[C@@H](O)[C@H](O)[C@@H]1O |r| |
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| Structure | 
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