| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
|---|
| Ligand | BDBM50442345 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_990951 (CHEMBL2445279) |
|---|
| IC50 | 40±n/a nM |
|---|
| Citation |  Kato, A; Okaki, T; Ifuku, S; Sato, K; Hirokami, Y; Iwaki, R; Kamori, A; Nakagawa, S; Adachi, I; Kiria, PG; Onomura, O; Minato, D; Sugimoto, K; Matsuya, Y; Toyooka, N Synthesis and biological evaluation of N-(2-fluorophenyl)-2ß-deoxyfuconojirimycin acetamide as a potent inhibitor fora-l-fucosidases. Bioorg Med Chem21:6565-73 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tissue alpha-L-fucosidase |
|---|
| Name: | Tissue alpha-L-fucosidase |
|---|
| Synonyms: | Alpha-L-fucosidase 1 | FUCA1 | FUCO_BOVIN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54093.12 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_335897 |
|---|
| Residue: | 468 |
|---|
| Sequence: | MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAK
FGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNP
DSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNI
RYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPD
TYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCT
SIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLA
VGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTT
KVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
|
|
|
|---|
| BDBM50442345 |
|---|
| n/a |
|---|
| Name | BDBM50442345 |
|---|
| Synonyms: | CHEMBL2442782 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H22N2O4 |
|---|
| Mol. Mass. | 294.3462 |
|---|
| SMILES | C[C@@H]1N[C@H](CC(=O)Nc2cccc(C)c2)[C@@H](O)[C@H](O)[C@@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
