| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1B1 |
|---|
| Ligand | BDBM50442877 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1265864 (CHEMBL3039490) |
|---|
| Ki | 800±n/a nM |
|---|
| Citation |  De Bruyn, T; van Westen, GJ; Ijzerman, AP; Stieger, B; de Witte, P; Augustijns, PF; Annaert, PP Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol83:1257-67 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier organic anion transporter family member 1B1 |
|---|
| Name: | Solute carrier organic anion transporter family member 1B1 |
|---|
| Synonyms: | LST1 | OATP1B1 | OATP2 | OATPC | SLC21A6 | SLCO1B1 | SO1B1_HUMAN | Solute carrier organic anion transporter family member 1B1 | Solute carrier organic anion transporter family member 1B1 (OATP1B1) | Thromboxane B2 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 76468.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9Y6L6 |
|---|
| Residue: | 691 |
|---|
| Sequence: | MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE
ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY
YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML
RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV
DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE
TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF
KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS
FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT
YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI
QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI
KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE
NGSVMDEANLESLNKNKHFVPSAGADSETHC
|
|
|
|---|
| BDBM50442877 |
|---|
| n/a |
|---|
| Name | BDBM50442877 |
|---|
| Synonyms: | METHYL 6-ACETOXYANGOLENSATE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H36O9 |
|---|
| Mol. Mass. | 528.5907 |
|---|
| SMILES | COC(=O)C(OC(C)=O)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@]34CC(=O)O[C@@H](c5ccoc5)[C@]3(C)CC[C@@H](C4=C)[C@]12C |r,TLB:35:34:31.32.29:16.36.17| |
|---|
| Structure | 
|
|---|
Search and Browse
