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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50443102 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1276332 (CHEMBL3089794) | ||
| Ki | 23±n/a nM | ||
| Citation |  Shonberg, J; Herenbrink, CK; López, L; Christopoulos, A; Scammells, PJ; Capuano, B; Lane, JR A structure-activity analysis of biased agonism at the dopamine D2 receptor. J Med Chem56:9199-221 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
| Type: | Cell-surface receptors | ||
| Mol. Mass.: | 50647.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14416 | ||
| Residue: | 443 | ||
| Sequence: |
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| BDBM50443102 | |||
| n/a | |||
| Name | BDBM50443102 | ||
| Synonyms: | CHEMBL3085819 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H27N3O | ||
| Mol. Mass. | 325.4479 | ||
| SMILES | CC(=O)N[C@H]1CC[C@H](CCN2CCc3ccc(cc3C2)C#N)CC1 |r,wU:4.3,wD:7.7,(83.78,-17.14,;82.45,-16.37,;82.45,-14.83,;81.11,-17.14,;79.78,-16.37,;78.44,-17.13,;77.12,-16.37,;77.12,-14.82,;75.78,-14.05,;74.45,-14.83,;73.12,-14.06,;73.11,-12.51,;71.76,-11.73,;70.43,-12.52,;69.09,-11.76,;67.76,-12.53,;67.76,-14.07,;69.1,-14.84,;70.43,-14.07,;71.77,-14.84,;66.43,-14.84,;65.1,-15.61,;78.44,-14.05,;79.78,-14.83,)| | ||
| Structure | 
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