| Reaction Details |
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 | Report a problem with these data |
| Target | Endothelial lipase |
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| Ligand | BDBM50443625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1279835 (CHEMBL3095694) |
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| IC50 | 31±n/a nM |
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| Citation |  Abdel-Magid, AF Endothelial lipase inhibitors for the treatment of atherosclerosis and cardiovascular disorders. ACS Med Chem Lett4:1016-7 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Endothelial lipase |
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| Name: | Endothelial lipase |
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| Synonyms: | EDL | Endothelial cell-derived lipase | Endothelial lipase | Endothelial lipase (EL) | LIPE_MOUSE | Lipg |
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| Type: | Protein |
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| Mol. Mass.: | 56643.58 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q9WVG5 |
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| Residue: | 500 |
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| Sequence: | MRNTVFLLGFWSVYCYFPAGSITTLRPQGSLRDEHHKPTGVPATARPSVAFNIRTSKDPE
QEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQMREKDANVVV
VDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGYSLGAHVAGYAGN
FVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHID
IYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDS
SRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFKVYHYQLKVHMFSYNN
SGDTQPTLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEDLGDLLKMRLTWEGVA
HSWYNLWNEFRNYLSQPSNPSRELYIRRIRVKSGETQRKVTFCTQDPTKSSISPGQELWF
HKCQDGWKMKNKTSPFVNLA
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| BDBM50443625 |
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| n/a |
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| Name | BDBM50443625 |
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| Synonyms: | CHEMBL3092448 | US9216998, 25 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16F3NO |
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| Mol. Mass. | 331.3316 |
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| SMILES | FC(F)(F)c1c(CCc2ccccc2)n2CCOc3cccc1c23 |
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| Structure | 
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