| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2X purinoceptor 3 |
|---|
| Ligand | BDBM86478 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1280014 (CHEMBL3096841) |
|---|
| IC50 | 35±n/a nM |
|---|
| Citation |  Cho, JH; Jung, KY; Jung, Y; Kim, MH; Ko, H; Park, CS; Kim, YC Design and synthesis of potent and selective P2X3 receptor antagonists derived from PPADS as potential pain modulators. Eur J Med Chem70:811-30 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2X purinoceptor 3 |
|---|
| Name: | P2X purinoceptor 3 |
|---|
| Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 44292.02 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P56373 |
|---|
| Residue: | 397 |
|---|
| Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
|
|
|
|---|
| BDBM86478 |
|---|
| n/a |
|---|
| Name | BDBM86478 |
|---|
| Synonyms: | A-317491 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H27NO8 |
|---|
| Mol. Mass. | 565.5694 |
|---|
| SMILES | OC(=O)c1cc(C(O)=O)c(cc1C(O)=O)C(=O)N(Cc1cccc(Oc2ccccc2)c1)[C@H]1CCCc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
