| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM50444485 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1277497 (CHEMBL3096017) |
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| Ki | 55±n/a nM |
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| Citation |  Ruel, R; L'Heureux, A; Thibeault, C; Lapointe, P; Martel, A; Qiao, JX; Hua, J; Price, LA; Wu, Q; Chang, M; Zheng, J; Huang, CS; Wexler, RR; Rehfuss, R; Lam, PY Potent P2Y1 urea antagonists bearing various cyclic amine scaffolds. Bioorg Med Chem Lett23:6825-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50444485 |
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| n/a |
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| Name | BDBM50444485 |
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| Synonyms: | CHEMBL3092620 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H25F3N4O3 |
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| Mol. Mass. | 534.529 |
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| SMILES | FC(F)(F)Oc1ccc(NC(=O)Nc2cccnc2Oc2cccc3CN(Cc4ccccc4)CCc23)cc1 |
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| Structure | 
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