| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-7 |
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| Ligand | BDBM50444601 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1282442 (CHEMBL3100743) |
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| Ki | 15000±n/a nM |
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| Citation |  Tan, X; Bertonati, C; Qin, L; Furio, L; El Amri, C; Hovnanian, A; Reboud-Ravaux, M; Villoutreix, BO Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins. Eur J Med Chem70:661-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-7 |
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| Name: | Kallikrein-7 |
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| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27535.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469257 |
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| Residue: | 253 |
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| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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| BDBM50444601 |
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| n/a |
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| Name | BDBM50444601 |
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| Synonyms: | CHEMBL3099881 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H16F3N5OS |
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| Mol. Mass. | 467.466 |
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| SMILES | Nc1ccc2nc(SCc3nc4ccccc4c(=O)n3-c3cccc(c3)C(F)(F)F)[nH]c2c1 |
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| Structure | 
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