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TargetKallikrein-5 [D153N]
LigandBDBM50444603
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1282456 (CHEMBL3100883)
IC50 117000±n/a nM
Citation Tan, XBertonati, CQin, LFurio, LEl Amri, CHovnanian, AReboud-Ravaux, MVilloutreix, BO Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins. Eur J Med Chem70:661-8 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kallikrein-5 [D153N]
Name:Kallikrein-5 [D153N]
Synonyms:KLK-L2 | KLK5 | KLK5_HUMAN | Kallikrein 5 | Kallikrein-5 | Kallikrein-like protein 2 | SCTE | Stratum corneum tryptic enzyme
Type:PROTEIN
Mol. Mass.:32031.75
Organism:Homo sapiens (Human)
Description:ChEMBL_1282456
Residue:293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
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  Blast E-value cutoff:
BDBM50444603
n/a
NameBDBM50444603
Synonyms:CHEMBL3099871
TypeSmall organic molecule
Emp. Form.C18H16N2O4
Mol. Mass.324.3306
SMILESCCOc1cc(\C=C(\C#N)C(=O)Nc2ccc(O)cc2)ccc1O
Structure
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