| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-1 |
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| Ligand | BDBM50444901 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1282983 (CHEMBL3100302) |
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| IC50 | 770±n/a nM |
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| Citation |  Hasegawa, M; Yasuda, Y; Tanaka, M; Nakata, K; Umeda, E; Wang, Y; Watanabe, C; Uetake, S; Kunoh, T; Shionyu, M; Sasaki, R; Shiina, I; Mizukami, T A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem71:290-305 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-1 |
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| Name: | Proteasome subunit beta type-1 |
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| Synonyms: | PSB1_HUMAN | PSC5 | PSMB1 | Proteasome component C5 | Proteasome subunit beta type-1/beta type-5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26493.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1366691 |
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| Residue: | 241 |
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| Sequence: | MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEG
FSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAML
STILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQ
VGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRK
D
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|
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| BDBM50444901 |
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| n/a |
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| Name | BDBM50444901 |
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| Synonyms: | CHEMBL3099638 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H46N2O2 |
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| Mol. Mass. | 478.7091 |
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| SMILES | CC(C)(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1 |
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| Structure | 
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