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TargetProteasome subunit beta type-2
LigandBDBM50444909
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1282984 (CHEMBL3100303)
IC50 340±n/a nM
Citation Hasegawa, MYasuda, YTanaka, MNakata, KUmeda, EWang, YWatanabe, CUetake, SKunoh, TShionyu, MSasaki, RShiina, IMizukami, T A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem71:290-305 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Proteasome subunit beta type-2
Name:Proteasome subunit beta type-2
Synonyms:20S proteasome | PSB2_HUMAN | PSMB2 | Proteasome Macropain subunit
Type:PROTEIN
Mol. Mass.:22837.53
Organism:Homo sapiens (Human)
Description:ChEMBL_1294233
Residue:201
Sequence:
MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYI
QKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDY
LAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSV
RIIDKNGIHDLDNISFPKQGS
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  Blast E-value cutoff:
BDBM50444909
n/a
NameBDBM50444909
Synonyms:CHEMBL3099618
TypeSmall organic molecule
Emp. Form.C38H50N2O2
Mol. Mass.566.8158
SMILES[#6]-[#6]\[#6](=[#6](/c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1)-c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1)-c1ccccc1
Structure
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