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TargetPurinergic receptor P2Y12
LigandBDBM50445011
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1281874
IC50 290±n/a nM
Citation Tu WFan JZhang HXu GLiu ZQu JYang FZhang LLuan TYuan JGong AFeng JSun PDong Q Synthesis and biological evaluation of cyclopentyl-triazolol-pyrimidine (CPTP) based P2Y12 antagonists. Bioorg Med Chem Lett 24:141-6 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Purinergic receptor P2Y12
Name:Purinergic receptor P2Y12
Synonyms:P2Y purinoceptor 12 | P2Y12
Type:PROTEIN
Mol. Mass.:39068.50
Organism:Rattus norvegicus
Description:ChEMBL_1454020
Residue:343
Sequence:
MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIR
SKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISF
LGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITK
CSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRV
NIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLD
PFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50445011
n/a
NameBDBM50445011
Synonyms:CHEMBL3098241
TypeSmall organic molecule
Emp. Form.C21H23F3N6O3S
Mol. Mass.496.506
SMILESCCCSc1nc(N[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c2nnn([C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H]3F)c2n1 |r|
Structure
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