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TargetNUAK family SNF1-like kinase 1
LigandBDBM50445472
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1284307 (CHEMBL3108328)
IC50 29800±n/a nM
Citation El Amrani, MLai, DDebbab, AAly, AHSiems, KSeidel, CSchnekenburger, MGaigneaux, ADiederich, MFeger, DLin, WProksch, P Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum. J Nat Prod77:49-56 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
NUAK family SNF1-like kinase 1
Name:NUAK family SNF1-like kinase 1
Synonyms:ARK5 | KIAA0537 | NUAK1 | NUAK1_HUMAN | OMPHK1
Type:PROTEIN
Mol. Mass.:74326.51
Organism:Homo sapiens (Human)
Description:ChEMBL_1451343
Residue:661
Sequence:
MEGAAAPVAGDRPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQET
LGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYE
VFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLK
LENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALG
VLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDI
ANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEV
MLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGV
VGPALPSTFKMEQDLCRTGVLLPSSPEAEVPGKLSPKQSATMPKKGILKKTQQRESGYYS
SPERSESSELLDSNDVMGSSIPSPSPPDPARVTSHSLSCRRKGILKHSSKYSAGTMDPAL
VSPEMPTLESLSEPGVPAEGLSRSYSRPSSVISDDSVLSSDSFDLLDLQENRPARQRIRS
CVSAENFLQIQDFEGLQNRPRPQYLKRYRNRLADSSFSLLTDMDDVTQVYKQALEICSKL
N
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50445472
n/a
NameBDBM50445472
Synonyms:CHEMBL3104852
TypeSmall organic molecule
Emp. Form.C10H10O6
Mol. Mass.226.1828
SMILESCOC1OC(=O)c2c1c(C)c(O)c(O)c2O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: