| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase Nek6 |
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| Ligand | BDBM50445474 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1284299 (CHEMBL3108320) |
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| IC50 | 1850±n/a nM |
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| Citation |  El Amrani, M; Lai, D; Debbab, A; Aly, AH; Siems, K; Seidel, C; Schnekenburger, M; Gaigneaux, A; Diederich, M; Feger, D; Lin, W; Proksch, P Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum. J Nat Prod77:49-56 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase Nek6 |
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| Name: | Serine/threonine-protein kinase Nek6 |
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| Synonyms: | NEK kinase | NEK6 | NEK6_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35724.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1446777 |
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| Residue: | 313 |
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| Sequence: | MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVY
KATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNI
VLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFI
TATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEM
AALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVH
QVAKQMHIWMSST
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| BDBM50445474 |
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| n/a |
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| Name | BDBM50445474 |
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| Synonyms: | CHEMBL3104855 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14O8 |
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| Mol. Mass. | 358.299 |
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| SMILES | Cc1c(O)c(O)c2oc(cc2c1C=O)-c1c(C)c(O)c(O)c(O)c1C=O |
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| Structure | 
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