| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 1 |
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| Ligand | BDBM50446072 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1283755 (CHEMBL3108480) |
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| IC50 | 69600±n/a nM |
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| Citation |  Tian, M; Abdelrahman, A; Weinhausen, S; Hinz, S; Weyer, S; Dosa, S; El-Tayeb, A; Müller, CE Carbamazepine derivatives with P2X4 receptor-blocking activity. Bioorg Med Chem22:1077-88 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 1 |
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| Name: | P2X purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RX1 | P2RX1_HUMAN | P2X1 | Purinergic receptor | Purinergic, P2X |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44992.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purinergic, P2X 0 HUMAN::P51575 |
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| Residue: | 399 |
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| Sequence: | MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSG
LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH
PEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESG
QNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVEN
GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
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| BDBM50446072 |
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| n/a |
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| Name | BDBM50446072 |
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| Synonyms: | CHEMBL3103369 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22N2O |
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| Mol. Mass. | 318.4122 |
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| SMILES | O=C(NC1CCCCC1)N1c2ccccc2C=Cc2ccccc12 |c:18| |
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| Structure | 
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