| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 4 |
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| Ligand | BDBM50446069 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1283887 (CHEMBL3106338) |
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| IC50 | 123000±n/a nM |
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| Citation |  Tian, M; Abdelrahman, A; Weinhausen, S; Hinz, S; Weyer, S; Dosa, S; El-Tayeb, A; Müller, CE Carbamazepine derivatives with P2X4 receptor-blocking activity. Bioorg Med Chem22:1077-88 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 4 |
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| Name: | P2X purinoceptor 4 |
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| Synonyms: | ATP receptor | P2RX4_MOUSE | P2rx4 | P2x4 | Purinergic receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43443.55 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1283887 |
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| Residue: | 388 |
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| Sequence: | MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIP
DKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAG
HSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYY
RDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYC
MKKRYYYRDKKYKYVEDYEQGLSGEMNQ
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| BDBM50446069 |
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| n/a |
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| Name | BDBM50446069 |
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| Synonyms: | CHEMBL3103372 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2O |
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| Mol. Mass. | 290.359 |
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| SMILES | O=C(N1CCCC1)N1c2ccccc2C=Cc2ccccc12 |c:16| |
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| Structure | 
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