Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 6-phospho-1-fructokinase | ||
| Ligand | BDBM50446120 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1288121 | ||
| IC50 | 2910±n/a nM | ||
| Citation |  Brimacombe KR; Walsh MJ; Liu L; Vásquez-Valdivieso MG; Morgan HP; McNae I; Fothergill-Gilmore LA; Michels PA; Auld DS; Simeonov A; Walkinshaw MD; Shen M; Boxer MB Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett 5:12-7 (2014) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 6-phospho-1-fructokinase | |||
| Name: | 6-phospho-1-fructokinase | ||
| Synonyms: | n/a | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 53537.94 | ||
| Organism: | Trypanosoma brucei | ||
| Description: | ChEMBL_1288121 | ||
| Residue: | 487 | ||
| Sequence: |
| ||
| BDBM50446120 | |||
| n/a | |||
| Name | BDBM50446120 | ||
| Synonyms: | CHEMBL3108839 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H17Cl2N3O4S | ||
| Mol. Mass. | 454.327 | ||
| SMILES | CN(c1cc(C)on1)S(=O)(=O)c1ccc(NC(=O)Cc2ccc(Cl)c(Cl)c2)cc1 | ||
| Structure | 
| ||