| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-7 |
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| Ligand | BDBM50446228 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1287998 (CHEMBL3110697) |
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| Ki | 2400±n/a nM |
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| Citation |  Oliveira, JP; Freitas, RF; Melo, LS; Barros, TG; Santos, JA; Juliano, MA; Pinheiro, S; Blaber, M; Juliano, L; Muri, EM; Puzer, L Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7. ACS Med Chem Lett5:128-32 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-7 |
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| Name: | Kallikrein-7 |
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| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27535.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469257 |
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| Residue: | 253 |
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| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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| BDBM50446228 |
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| n/a |
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| Name | BDBM50446228 |
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| Synonyms: | CHEMBL3109061 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H49N5O10 |
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| Mol. Mass. | 759.8446 |
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| SMILES | [#6]C([#6])([#6])[#8]-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#8]-[#6@@H]-2-[#6@@H](-[#6]-[#8]-[#6@H]-1-2)-[#8]-[#6]-c1ccccc1 |r| |
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| Structure | 
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