| Reaction Details |
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 | Report a problem with these data |
| Target | Complement factor D |
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| Ligand | BDBM50446396 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1287129 (CHEMBL3111918) |
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| IC50 | 3.0±n/a nM |
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| Citation |  Abdel-Magid, AF Inhibitors of factor d may provide a treatment for age-related macular degeneration. ACS Med Chem Lett5:106-7 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Complement factor D |
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| Name: | Complement factor D |
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| Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
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| Type: | Protein |
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| Mol. Mass.: | 27039.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00746 |
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| Residue: | 253 |
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| Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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| BDBM50446396 |
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| n/a |
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| Name | BDBM50446396 |
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| Synonyms: | CHEMBL3109654 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19IN6O3 |
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| Mol. Mass. | 530.3184 |
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| SMILES | NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(I)n2)c2ccccc12 |r| |
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| Structure | 
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