| Reaction Details |
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 | Report a problem with these data |
| Target | Cholinesterase |
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| Ligand | BDBM50447019 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1289180 (CHEMBL3119242) |
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| IC50 | >10000±n/a nM |
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| Citation |  González-Naranjo, P; Pérez-Macias, N; Campillo, NE; Pérez, C; Arán, VJ; Girón, R; Sánchez-Robles, E; Martín, MI; Gómez-Cañas, M; García-Arencibia, M; Fernández-Ruiz, J; Páez, JA Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease. Eur J Med Chem73:56-72 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholinesterase |
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| Name: | Cholinesterase |
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| Synonyms: | BCHE | Butyrylcholinesterase (BuChE) | CHLE_HORSE | Cholinesterase |
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| Type: | Enzyme |
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| Mol. Mass.: | 65643.35 |
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| Organism: | Equus caballus (Horse) |
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| Description: | P81908 |
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| Residue: | 574 |
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| Sequence: | EEDIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSNIWNATK
YANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQT
GTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQK
NIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEAR
NRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLT
DMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPR
VSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTRKFSELGNDAFFYY
FEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMKRWANFAKYGNP
NGTQNNSTRWPVFKSTEQKYLTLNTESPKVYTKLRAQQCRFWTLFFPKVLELTGNIDEAE
REWKAGFHRWNNYMMDWKNQFNDYTSKKESCSDF
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| BDBM50447019 |
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| n/a |
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| Name | BDBM50447019 |
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| Synonyms: | CHEMBL3116295 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N4O4 |
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| Mol. Mass. | 432.4718 |
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| SMILES | [O-][N+](=O)c1ccc2n(CCN3CCOCC3)nc(OCc3ccc4ccccc4c3)c2c1 |
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| Structure | 
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