| Reaction Details |
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 | Report a problem with these data |
| Target | Oxa40 |
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| Ligand | BDBM50447647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1289443 (CHEMBL3117137) |
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| IC50 | 28000±n/a nM |
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| Citation |  Blizzard, TA; Chen, H; Kim, S; Wu, J; Bodner, R; Gude, C; Imbriglio, J; Young, K; Park, YW; Ogawa, A; Raghoobar, S; Hairston, N; Painter, RE; Wisniewski, D; Scapin, G; Fitzgerald, P; Sharma, N; Lu, J; Ha, S; Hermes, J; Hammond, ML Discovery of MK-7655, aß-lactamase inhibitor for combination with Primaxin®. Bioorg Med Chem Lett24:780-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxa40 |
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| Name: | Oxa40 |
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| Synonyms: | Beta-lactamase | Class D β-lactamase (OXA-24) |
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| Type: | Enzyme |
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| Mol. Mass.: | 30946.50 |
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| Organism: | Acinetobacter baumannii |
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| Description: | Q8RLA6 |
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| Residue: | 275 |
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| Sequence: | MKKFILPIFSISILVSLSACSSIKTKSEDNFHISSQQHEKAIKSYFDEAQTQGVIIIKEG
KNLSTYGNALARANKEYVPASTFKMLNALIGLENHKATTNEIFKWDGKKRTYPMWEKDMT
LGEAMALSAVPVYQELARRTGLELMQKEVKRVNFGNTNIGTQVDNFWLVGPLKITPVQEV
NFADDLAHNRLPFKLETQEEVKKMLLIKEVNGSKIYAKSGWGMGVTPQVGWLTGWVEQAN
GKKIPFSLNLEMKEGMSGSIRNEITYKSLENLGII
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| BDBM50447647 |
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| n/a |
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| Name | BDBM50447647 |
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| Synonyms: | CHEMBL3112752 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20N4O8S |
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| Mol. Mass. | 428.417 |
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| SMILES | N[C@@H](Cc1ccc(NC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3OS(O)(=O)=O)cc1)C(O)=O |r| |
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| Structure | 
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