Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Protein-arginine deiminase type-2 | ||
| Ligand | BDBM50447758 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1290379 (CHEMBL3119094) | ||
| IC50 | 26100±n/a nM | ||
| Citation |  Dreyton, CJ; Anderson, ED; Subramanian, V; Boger, DL; Thompson, PR Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation. Bioorg Med Chem22:1362-9 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Protein-arginine deiminase type-2 | |||
| Name: | Protein-arginine deiminase type-2 | ||
| Synonyms: | KIAA0994 | PAD-H19 | PAD2 | PADI2 | PADI2_HUMAN | PDI2 | Peptidylarginine deiminase II | Protein-arginine deiminase type II | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 75552.49 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1290379 | ||
| Residue: | 665 | ||
| Sequence: |
| ||
| BDBM50447758 | |||
| n/a | |||
| Name | BDBM50447758 | ||
| Synonyms: | CHEBI:9287 | NSC-45383 | Nigrin | Rufocromomycin | Streptonigrin | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H22N4O8 | ||
| Mol. Mass. | 506.4642 | ||
| SMILES | COC1=C(N)C(=O)c2nc(ccc2C1=O)-c1nc(C(O)=O)c(C)c(c1N)-c1ccc(OC)c(OC)c1O |c:2,(25.46,-.06,;26.8,-.83,;28.13,-.06,;28.13,1.48,;26.79,2.25,;29.46,2.25,;29.46,3.79,;30.79,1.49,;32.13,2.25,;33.46,1.48,;33.46,-.05,;32.14,-.83,;30.79,-.06,;29.47,-.83,;29.47,-2.37,;34.79,2.25,;36.13,1.48,;37.47,2.26,;38.8,1.49,;40.13,2.26,;38.81,-.05,;37.46,3.79,;38.79,4.57,;36.13,4.55,;34.79,3.79,;33.46,4.56,;36.13,6.09,;37.46,6.86,;37.46,8.42,;36.12,9.19,;36.12,10.73,;37.45,11.5,;34.8,8.42,;33.46,9.18,;33.46,10.72,;34.79,6.86,;33.46,6.09,)| | ||
| Structure | 
| ||