| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-arginine deiminase type-1 |
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| Ligand | BDBM80075 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1290380 |
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| IC50 | 4550±n/a nM |
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| Citation |  Dreyton CJ; Anderson ED; Subramanian V; Boger DL; Thompson PR Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation. Bioorg Med Chem 22:1362-9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-arginine deiminase type-1 |
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| Name: | Protein-arginine deiminase type-1 |
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| Synonyms: | Peptidylarginine deiminase I | Protein-arginine deiminase type I |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74664.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1290380 |
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| Residue: | 663 |
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| Sequence: | MAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVK
EPIGKARWPLDTDADMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLE
VDTGRTGKVKRSQGDKKTWRWGPEGYGAILLVNCDRDNHRSAEPDLTHSWLMSLADLQDM
SPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCLSYEVER
QPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGTLPEVTLFTDTVGFRMAPWIMTPNT
QPPEELYVCRVMDTHGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEFGYIE
APHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYVTREIPLPGPSSLDSFGNLDVSPPVTV
GGTEYPLGRILIGSSFPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVDEFLTFV
PTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRHLQRDN
LHAQKCIDWNRNVLKRELGLAESDIVDIPQLFFLKNFYAEAFFPDMVNMVVLGKYLGIPK
PYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYLSYHELQGEIHCGTNVRRKPFPFKWWN
MVP
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| BDBM80075 |
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| n/a |
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| Name | BDBM80075 |
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| Synonyms: | 7-bromanyl-6-methoxy-quinoline-5,8-dione | 7-bromo-6-methoxy-quinoline-5,8-quinone | 7-bromo-6-methoxyquinoline-5,8-dione | MLS002703741 | SMR001570458 | cid_265935 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H6BrNO3 |
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| Mol. Mass. | 268.064 |
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| SMILES | COC1=C(Br)C(=O)c2ncccc2C1=O |c:2| |
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| Structure | 
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