| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholine receptor subunit epsilon |
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| Ligand | BDBM50448370 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1292388 (CHEMBL3123981) |
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| IC50 | 7943±n/a nM |
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| Citation |  Matera, C; Flammini, L; Quadri, M; Vivo, V; Ballabeni, V; Holzgrabe, U; Mohr, K; De Amici, M; Barocelli, E; Bertoni, S; Dallanoce, C Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity. Eur J Med Chem75:222-32 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholine receptor subunit epsilon |
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| Name: | Acetylcholine receptor subunit epsilon |
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| Synonyms: | ACHE_RAT | Acetylcholine receptor protein epsilon chain | Achre | Chrne |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54930.09 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1292388 |
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| Residue: | 494 |
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| Sequence: | MTMALLGTLLLLALFGRSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNL
ISLNEKEETLTTSVWIGIEWQDYRLNFSKDDFAGVEILRVPSEHVWLPEIVLENNIDGQF
GVAYDCNVLVYEGGSVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVELIF
AVDDDGNAINKIDIDTAAFTENGEWAIDYCPGMIRHYEGGSTEDPGETDVIYTLIIRRKP
LFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLS
VPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHATSPRLRQILLELLPRLLGLSPPP
EDPGAASPARRASSVGILLRAEELILKKPRSELVFEGQRHRHGTWTAAALCQNLGAAAPE
VRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYF
NQVPDLPYPPCIQP
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| BDBM50448370 |
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| n/a |
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| Name | BDBM50448370 |
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| Synonyms: | CHEMBL3120178 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H46N4O4 |
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| Mol. Mass. | 562.7416 |
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| SMILES | C[N+](C)(CCCCCCC[N+](C)(C)CC#CCOC1=NOCC1)CCCN1C(=O)c2cccc3cccc(C1=O)c23 |t:18| |
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| Structure | 
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