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TargetAldehyde dehydrogenase 3A1 (ALDH3A1)
LigandBDBM50448790
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1295316
IC50 360±n/a nM
Citation Kimble-Hill ACParajuli BChen CHMochly-Rosen DHurley TD Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones. J Med Chem 57:714-22 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Aldehyde dehydrogenase 3A1 (ALDH3A1)
Name:Aldehyde dehydrogenase 3A1 (ALDH3A1)
Synonyms:Aldehyde dehydrogenase family 3 member A1 (ALDH3A1) | Aldehyde dehydrogenase family 3 member A1 (ALDH3A1) (Q122A)
Type:Protein
Mol. Mass.:50394.38
Organism:Homo sapiens (Human)
Description:n/a
Residue:453
Sequence:
MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
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  Blast E-value cutoff:
BDBM50448790
n/a
NameBDBM50448790
Synonyms:CHEMBL3128208
TypeSmall organic molecule
Emp. Form.C9H6BrNO2
Mol. Mass.240.053
SMILESCc1cc2C(=O)C(=O)Nc2c(Br)c1
Structure
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