Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Neuropeptide Y receptor type 5 | ||
Ligand | BDBM50449317 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1296657 (CHEMBL3131566) | ||
Ki | 720±n/a nM | ||
Citation | Burns, JF; Chen, B; Chen, CA; Doller, D; Edelmenky, E; Jiang, Y; Peterson, JM; Sabio, M; Weiss, J; White, AD; Wu, L; Bhardwaj, R; Chandrasena, G; Boyle, NJ; Huang, X cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonists. Bioorg Med Chem Lett24:1458-61 (2014) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neuropeptide Y receptor type 5 | |||
Name: | Neuropeptide Y receptor type 5 | ||
Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
Type: | Enzyme | ||
Mol. Mass.: | 50746.64 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q15761 | ||
Residue: | 445 | ||
Sequence: |
| ||
BDBM50449317 | |||
n/a | |||
Name | BDBM50449317 | ||
Synonyms: | CHEMBL3126054 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H23F2N3O2 | ||
Mol. Mass. | 399.4337 | ||
SMILES | Fc1cc(F)cc(c1)-c1ccc(NC(=O)[C@H]2CC[C@@H](CC2)N2CCCC2=O)nc1 |r,wU:18.22,wD:15.15,(19.4,-21.94,;20.17,-20.6,;19.4,-19.27,;20.17,-17.93,;19.4,-16.6,;21.71,-17.93,;22.48,-19.27,;21.71,-20.6,;24.02,-19.27,;24.79,-17.93,;26.33,-17.93,;27.1,-19.27,;28.64,-19.27,;29.41,-20.6,;28.71,-21.98,;30.94,-20.52,;31.78,-21.81,;33.32,-21.74,;34.02,-20.36,;33.18,-19.07,;31.64,-19.15,;35.56,-20.28,;36.4,-18.99,;37.88,-19.39,;37.97,-20.92,;36.53,-21.48,;36.12,-22.96,;26.33,-20.6,;24.79,-20.6,)| | ||
Structure |