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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50449320 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1296657 (CHEMBL3131566) | ||
| Ki | 10.0±n/a nM | ||
| Citation |  Burns, JF; Chen, B; Chen, CA; Doller, D; Edelmenky, E; Jiang, Y; Peterson, JM; Sabio, M; Weiss, J; White, AD; Wu, L; Bhardwaj, R; Chandrasena, G; Boyle, NJ; Huang, X cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonists. Bioorg Med Chem Lett24:1458-61 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50449320 | |||
| n/a | |||
| Name | BDBM50449320 | ||
| Synonyms: | CHEMBL3126050 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H26F2N4O2 | ||
| Mol. Mass. | 428.4749 | ||
| SMILES | CCN1CCN([C@H]2CC[C@H](CC2)C(=O)Nc2ccc(cn2)-c2cc(F)cc(F)c2)C1=O |r,wU:9.12,6.5,(35.65,-39.74,;34.26,-39.09,;33,-39.97,;32.97,-41.51,;31.5,-41.95,;30.61,-40.69,;29.07,-40.67,;28.27,-41.99,;26.73,-41.96,;25.99,-40.61,;26.78,-39.29,;28.32,-39.31,;24.45,-40.58,;23.7,-39.23,;23.65,-41.9,;22.11,-41.87,;21.32,-43.18,;19.78,-43.15,;19.03,-41.81,;19.83,-40.49,;21.37,-40.52,;17.49,-41.78,;16.75,-40.43,;15.21,-40.4,;14.47,-39.05,;14.41,-41.72,;15.16,-43.07,;14.36,-44.39,;16.7,-43.1,;31.54,-39.46,;31.09,-38,)| | ||
| Structure | 
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