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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50449329 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1296657 (CHEMBL3131566) | ||
| Ki | 5.0±n/a nM | ||
| Citation |  Burns, JF; Chen, B; Chen, CA; Doller, D; Edelmenky, E; Jiang, Y; Peterson, JM; Sabio, M; Weiss, J; White, AD; Wu, L; Bhardwaj, R; Chandrasena, G; Boyle, NJ; Huang, X cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonists. Bioorg Med Chem Lett24:1458-61 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50449329 | |||
| n/a | |||
| Name | BDBM50449329 | ||
| Synonyms: | CHEMBL3126046 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H22F2N4O2 | ||
| Mol. Mass. | 400.4218 | ||
| SMILES | Fc1cc(F)cc(c1)-c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)N2CCNC2=O)nc1 |r,wU:15.15,18.22,(13.81,-25.74,;14.58,-27.07,;13.81,-28.41,;14.58,-29.74,;13.81,-31.07,;16.12,-29.74,;16.89,-28.41,;16.12,-27.07,;18.43,-28.41,;19.2,-29.74,;20.74,-29.74,;21.51,-28.41,;23.05,-28.41,;23.82,-27.07,;23.05,-25.74,;25.36,-27.07,;26.13,-28.41,;27.67,-28.41,;28.44,-27.07,;27.67,-25.74,;26.13,-25.74,;29.98,-27.07,;30.88,-28.32,;32.35,-27.84,;32.35,-26.3,;30.88,-25.82,;30.41,-24.37,;20.74,-27.07,;19.2,-27.07,)| | ||
| Structure | 
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