Ki Summary

Reaction Details

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Target

Glycogen phosphorylase, muscle form

Ligand

BDBM50057725

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_70989 (CHEMBL680567)

346737±n/a nM

Citation

Pastor, M; Cruciani, G; Watson, KA A strategy for the incorporation of water molecules present in a ligand binding site into a three-dimensional quantitative structure--activity relationship analysis. J Med Chem40:4089-102 (1998) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Glycogen phosphorylase, muscle form

Name:

Glycogen phosphorylase, muscle form

Synonyms:

Glycogen phosphorylase, muscle form | Muscle glycogen phosphorylase | Myophosphorylase | PYGM | PYGM_HUMAN

Type:

PROTEIN

Mol. Mass.:

97097.45

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1449751

Residue:

842

Sequence:

MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEA
DDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVN
TMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERM
DWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFP
GDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKF
QNKTNGITPRRWLVLCNPGLAEVIAERIGEDFISDLDQLRKLLSFVDDEAFIRDVAKVKQ
ENKLKFAAYLEREYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFV
PRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPA
ADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVD
KLDQRGYNAQEYYDRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYED
YIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDE
AI

BDBM50057725

n/a

Name

BDBM50057725

Synonyms:

(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-carbamic acid benzyl ester | CHEMBL335891

Type

Small organic molecule

Emp. Form.

C14H19NO7

Mol. Mass.

313.3032

SMILES

[H][C@@]1(NC(=O)OCc2ccccc2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Structure