| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pancreatic triacylglycerol lipase |
|---|
| Ligand | BDBM24567 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_527250 (CHEMBL972810) |
|---|
| IC50 | 80.7±n/a nM |
|---|
| Citation |  Jiang, W; Li, W; Han, L; Liu, L; Zhang, Q; Zhang, S; Nikaido, T; Koike, K Biologically active triterpenoid saponins from Acanthopanax senticosus. J Nat Prod69:1577-81 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pancreatic triacylglycerol lipase |
|---|
| Name: | Pancreatic triacylglycerol lipase |
|---|
| Synonyms: | LIPP_HUMAN | PL | PNLIP | Pancreatic lipase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 51157.75 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_527250 |
|---|
| Residue: | 465 |
|---|
| Sequence: | MLPLWTLSLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTN
ENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCIC
VDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGR
RTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGH
LDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGF
PCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVS
VTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVKFIWY
NNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREEVLLTLTPC
|
|
|
|---|
| BDBM24567 |
|---|
| n/a |
|---|
| Name | BDBM24567 |
|---|
| Synonyms: | (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate | CHEMBL175247 | Orlistat | THLP | Tetrahydrolipstatin | US9328123, Orlistat | Xenical |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H53NO5 |
|---|
| Mol. Mass. | 495.7348 |
|---|
| SMILES | CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
